Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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CTSI-CN Leadership Statement

The CTSI-CN offers our heartfelt condolences to the family of George Floyd and all victims of racism and prejudice. Our mission is to advance the health and well-being of our community, including its minority and underserved populations.

We will listen, we will learn, and we will think creatively about how research initiatives can help move us towards solutions.

Most importantly, we will not turn away. We will be present to support our researchers and our communities through this difficult time in our city and our nation.

  • Dec
    Thu, 12/10/2020 - 15:00 to 16:00

    ResearchMatch is a free participant recruitment and feasibility analysis tool for researchers at participating institutions. The tool is offered to researchers who are conducting research which is health related.

  • Dec
    Fri, 12/11/2020 - 12:00 to 13:00

    Presenting research documenting how the COVID-19 pandemic has impacted the mental health of young people and describe local efforts.

  • Dec
    Mon, 12/14/2020 (All day) to Thu, 12/17/2020 (All day)

    The GW Gelman Library is offering a workshop on Python that will help you learn and practice the basics of programming such as: data types, loops, functions, working with numeric data, and plotting data.

CTSI-CN WINTER 2020: Proposals due on January 1, 2021!

Awards of up to $4K each are available for multidisciplinary research teams engaged in biomedical or community research aimed at translating discovery to improved health.  Research teams must include 2 or more independent investigators, with one designated as the PI for the entire application. The purpose of this voucher opportunity is to support research that will eventually lead to collaborative or multiple PI proposals. 

Learn more