Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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  • Jan
    24
    Thu, 01/24/2019 - 12:00 to 13:00
    The District of Columbia Intellectual & Developmental Disabilities Research Center (DC - IDDRC) hosts Dr. Peyman Golshani, MD, PhD of the University of California Los Angeles. 
  • Jan
    26
    Sat, 01/26/2019 (All day) to Sun, 01/27/2019 (All day)
    CTSI is co-sponsoring the January 26-27 Annual Medical Solutions Hackathon, organized by George Hacks. This 24-hour hackathon is open to undergraduates of any college or university. Three Info sessions are being offered, and registration is required by January 22, 2019. 
  • Jan
    28
    Mon, 01/28/2019 - 12:00 to 13:00
    This month, the Health Disparities SIG will discuss Embedding Racial Equity in a Decentralized Network, presented by members of the Early Childhood Innovation Network’s Racial Equity Council. 
  • Jan
    31
    Thu, 01/31/2019 - 12:00 to 13:00
    Children's National faculty are invited to an interactive game of JEOPARDY on Business Intelligence(BI) and grants management.
  • Feb
    7
    Thu, 02/07/2019 (All day) to Fri, 02/08/2019 (All day)
    The Opioid Crisis and the Future of Addiction and Pain Therapeutics: Opportunities, Tools, and Technologies Symposium will be held at the NIH campus in Bethesda, MD. Advanced registration is required. 
  • Feb
    14
    Thu, 02/14/2019 - 08:00 to 09:00


    We are pleased to invite you to TriNetX's monthly training for all users. During this session conducted by TriNetX's expert instructions, query development, inclusion and exclusion criteria, dependent events, results analysis and more will be covered.

  • Feb
    14
    Thu, 02/14/2019 - 12:00 to 13:00


    We are pleased to invite you to TriNetX's monthly training for all users. During this session conducted by TriNetX's expert instructions, query development, inclusion and exclusion criteria, dependent events, results analysis and more will be covered.

  • Feb
    14
    Thu, 02/14/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Feb
    26
    Tue, 02/26/2019 (All day) to Wed, 02/27/2019 (All day)
    On February 26-27, the Buffalo CTSI hosts Fostering An Evidence-Based Approach to Improving CTSA Network Capacity. Early registration for this 100% virtual workshop is just $50 and ends on January 31.
  • Mar
    4
    Mon, 03/04/2019 - 12:00 to 13:00
    Dr. Michael Lindsey will present on his research focused on mental health services for vulnerable youth as part of the Center for Translational Research’s Enrichment Series. Please email Leandra Godoy for details and to RSVP. 
  • Mar
    14
    Thu, 03/14/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Apr
    1
    Mon, 04/01/2019 (All day) to Fri, 04/05/2019 (All day)
    Each year, Children’s Research Institute (CRI), the academic arm of Children’s National Health System, showcases the scholarly achievements of our faculty, staff and trainees across all disciplines and the role they play in advancing medical science and providing the highest quality care for children. 
  • Apr
    8
    Mon, 04/08/2019 - 12:00 to 13:00


    Dee Henderson of PR & Marketing will discuss How to Package Yourself: What's on that bio? Kevin Grigsby of the AAMC will discuss team communication and conflict resolution as part of the WATCH Seminar Series. 

  • Apr
    9
    Tue, 04/09/2019 (All day) to Wed, 04/10/2019 (All day)
    GW Research Days showcases Research, Scholarship and Creative Endeavor at the George Washington University. 
  • Apr
    11
    Thu, 04/11/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • January 18th, 2019
    Martin Luther King Jr. day has become a recognized day of service. Click here to learn where you can serve. 
  • January 17th, 2019
    In today's blog, NIH Director Dr. Francis Collins discusses how NIH researchers are pairing AI analysis with smartphone cameras to help more women avoid cervical cancer. Read the full article HERE.  
  • January 15th, 2019
    In today's blog, NIH Director Dr. Francis Collins discusses the use of artifical intelligence to monitor and detect irregular heartbeats. "After just seven months of training, the computer-devised algorithm was as good—and in some cases even better than—cardiology experts at making the correct diagnostic call." Read the full article HERE.  
  • January 14th, 2019

    The CTSI-CN is accepting letters of intent for the Career Development Award until this Friday, January 18, 2019. All LOIs must be submitted by 5:00 pm EST. For more details and to download the RFA, please visit CTSI-CN Funding

  • January 12th, 2019

    Masters students in data science are encouraged to apply to the 2019 Graduate Data Science Summer Program, a partnership between the NIH Office of Training & Education and the newly formed Office of Data Science Strategy. 

  • January 4th, 2019

    Children's National faculty and staff must submit their abstracts by January 11, 2019 to be included in the 9th annual Research and Education Week. 

  • January 4th, 2019

    Submit your abstract by Feburary 28, 2019 to be included in a Showcase of Research, Scholarship and Creative Endeavor at the George Washington University.

  • December 31st, 2018

    A new Pathology and Laboratory Medicine Research Core is now available to the researchers of Children's National. 

  • December 14th, 2018

    The faculties of Children's National Health System and George Washington, Howard, and Georgetown universities can apply for the District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) pilot award. 

  • December 7th, 2018

    The Pilot and Translational Clinical (PTC) Studies module of the CTSI-CN announces the release of the 2019-2020 RFAs.  All high impact research relevant to health and well-being throughout the lifespan is eligible. Support is not limited to pediatric research. Letters of Intent are due January 4, 2019.

  • December 3rd, 2018
    The CD2H is excited to announce the launch of the CD2H Idea Competition. This is an opportunity to turn your scientific question into a DREAM Challenge to be tackled by teams around the world. If your idea is selected, you will receive a $100,000 subcontract to run the DREAM Challenge in collaboration with the CD2H. The deadline to submit your initial proposal is February 15, 2019. 
  • December 3rd, 2018

    The George Washington University is offering an online, 3-credit-hour, 30-CME course, Grantsmanship in Clinical and Translational Research. This 10-week course begins January 14, 2019 and will cover the complete process of research grant proposal development, from specific aims to preparation of a full proposal package for submission, with the NIH R01 as exemplar.

  • November 20th, 2018

    "In April 2018, NIH launched the HEAL (Helping to End Addiction Long-term) Initiative, an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis”. The HEAL website has listed funding opportunities that will become available in December.  

  • November 7th, 2018
    The CTSI-CN proudly announces the 2019 Healthcare Hackathon. You don't have to be a programmer to have an idea for healthcare software. Finalists will attend a half-day hackathon to develop their ideas into prototypes. Winners receive funding to bring their app to life. Ideas are due January 4, 2019.
  • October 23rd, 2018
     
    Volunteers needed for Discover SCIENCE with Dr. Bear, a series of free STEAM events at DC libraries this fall and winter. Children are invited to do science activities, art projects, and learn about health. Volunteers will engage attendees in conversation about science topics and assist with activites. 

Impact

Has the CTSI-CN has supported your research? Tell us about it here.  

Support Pediatric Research

Support care. Fund research. Improve lives. Children’s National takes on some of the most daunting medical research issues to improve children’s lives. Our experts develop therapies, find cures, and improve children's health in our community, across the nation, and around the world. Click here to learn more and offer your support for Pediatric Research at Children's National. Donations contribute to innovative research in a wide range of programs.